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Various

"Scientific American Supplement, No. 299, September 24, 1881"

Opium, champagne, hypodermic injections of
sulphuric ether, counter-irritation, etc., proved useless. The doctor
was on the point of injecting dilute liquor ammonii into the veins, but,
none being obtainable, it occurred to him to try nitrite of amyl as a
last resort. A considerable amount was poured on a handkerchief and held
before the patient's mouth and nose, while the legs were also rubbed
energetically with the same agent. Respiration soon became deeper and
more regular, while the pulse gradually returned at the wrist. These
procedures were repeated again and again, without regard to the quantity
of the drug used, as soon as the radial pulse became weaker, and kept
up until the patient complained of a sense of fullness in the head, and
requested the discontinuance of the drug. The evacuations became less
frequent, and in a week the patient was able to be up. Resuming then,
Kurz concludes that nitrite of amyl is indicated in cardiac affections
when the capillary circulation is obstructed and the cardiac muscle is
threatened with paralysis from overwork; further, in cases of impeded
circulation occasioned by cholera or severe diarrhea, particularly in
the so-called hydrocephaloid (false hydrocephalus) of children. It
is worthy of trial in tetanic and eclamptic seizures, and in tonic
angiospasms such as occur during the chill of malarial fevers, although
in the last-mentioned condition pilocarpine is perhaps more suitable,
provided the energy of the heart be unimpaired.


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