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Various

"Scientific American Supplement, No. 299, September 24, 1881"

But, upon the other
hand, it is accused of producing disorders, and even grave accidents in
almost all the functions of the economy. In some cases it has produced
ringing in the ears or deafness, or a rapid pulse, or an excessively
high temperature, panting respiration, profuse perspiration,
albuminuria, delirium, and imminent collapse. In one published case this
anti-pyretic did not lower, but, on the contrary, seemed actually to
raise the temperature so high that immediately after death it stood at
110 deg. F. Many, very many, analogous cases have been published. I repeat,
therefore, that I am personally unacquainted with the effects of this
medicine in acute articular rheumatism, and that I have not thus far
been tempted to employ it.
It may be difficult to see the connection between blisters and alkalies
in their power to influence the course of acute articular rheumatism,
and yet it is certain that they do so influence it, and in the same way,
_i. e._, by altering the condition of the blood from acid to alkaline.
If you ask me to explain to you how blisters act in this way I am
obliged to confess my ignorance. To produce this result they must be
applied over all the affected joints. Experience, if not science, has
decided conclusively in their favor.


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